systemic sclerosis - vertaling naar arabisch
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systemic sclerosis - vertaling naar arabisch

SCLERODERMA THAT IS CHARACTERIZED BY FIBROSIS (OR HARDENING) OF THE SKIN AND MAJOR ORGANS, AS WELL AS VASCULAR ALTERATIONS, AND AUTOANTIBODIES
Systemic sclerosis; Systemic Sclerosis in Greece; SSc; Progressive systemic sclerosis; Systemic sclerosis (scleroderma); Diffuse cutaneous type systemic sclerosis; Diffuse cutaneous systemic sclerosis
  • Fibroblasts

systemic sclerosis         
‎ تَصَلُّبٌ مَجْموعِيّ‎
progressive systemic sclerosis         
‎ تَصَلُّبٌ مَجْموعِيٌّ مُتَرَقٍّ‎
systemic scleroderma         
‎ تَصَلُّبُ الجِلْدِ المَجْموعِيّ‎

Definitie

multiple sclerosis

Wikipedia

Systemic scleroderma

Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse. The limited form affects areas below, but not above, the elbows and knees with or without involvement of the face. The diffuse form also affects the skin above the elbows and knees and can also spread to the torso. Visceral organs, including the kidneys, heart, lungs, and gastrointestinal tract can also be affected by the fibrotic process. Prognosis is determined by the form of the disease and the extent of visceral involvement. Patients with limited systemic sclerosis have a better prognosis than those with the diffuse form. Death is most often caused by lung, heart, and kidney involvement. The risk of cancer is increased slightly.

Survival rates have greatly increased with effective treatment for kidney failure. Therapies include immunosuppressive drugs, and in some cases, glucocorticoids.